COMLEX USA Comprehensive Osteopathic Medical Licensing Examination Practice 2026 - Free COMLEX Practice Questions and Study Guide

A hyperactive deep tendon reflex (DTR) response is classified as DTR Grade 3 or Grade 4, as these grades indicate an exaggerated response to stimuli, which is typically associated with upper motor neuron lesions or heightened neuromuscular excitability.

DTR Grade 3 denotes a brisk response that is still within normal limits but is enhanced compared to a typical reflex. This can suggest a mild degree of hyperactivity. In contrast, DTR Grade 4 is characterized by a very brisk reflex response and can be accompanied by clonus, which indicates a significantly heightened level of neural excitability associated with more severe neurological conditions.

Understanding the grading system of deep tendon reflexes is important for assessing neurological function. In a clinical context, finding a patient with a hyperactive reflex assists healthcare providers in narrowing down potential central nervous system issues or conditions affecting the nervous system as a whole.